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Cholesterol Oxidase Is Indispensable in the Pathogenesis of Mycobacterium tuberculosis

Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular enzyme capable of converting cholesterol to its 3-keto-4-ene derivative, cholestenone, has been proposed to play a role in the vir...

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Detalhes bibliográficos
Main Authors: Klink, Magdalena, Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767793/
https://ncbi.nlm.nih.gov/pubmed/24039915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073333
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