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Cholesterol Oxidase Is Indispensable in the Pathogenesis of Mycobacterium tuberculosis

Despite considerable research effort, the molecular mechanisms of Mycobacterium tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular enzyme capable of converting cholesterol to its 3-keto-4-ene derivative, cholestenone, has been proposed to play a role in the vir...

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Détails bibliographiques
Auteurs principaux: Klink, Magdalena, Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767793/
https://ncbi.nlm.nih.gov/pubmed/24039915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073333
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