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Cholesterol Oxidase Binds TLR2 and Modulates Functional Responses of Human Macrophages

Cholesterol oxidase (ChoD) is considered to be an important virulence factor for Mycobacterium tuberculosis (Mtb), but its influence on macrophage activity is unknown. Here we used Nocardia erythropolis ChoD, which is very similar to the Mtb enzyme (70% identity at the amino-acid level), to evaluate...

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Detalhes bibliográficos
Main Authors: Bednarska, Katarzyna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw, Klink, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121183/
https://ncbi.nlm.nih.gov/pubmed/25120288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/498395
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