Cholesterol Oxidase Binds TLR2 and Modulates Functional Responses of Human Macrophages

Cholesterol oxidase (ChoD) is considered to be an important virulence factor for Mycobacterium tuberculosis (Mtb), but its influence on macrophage activity is unknown. Here we used Nocardia erythropolis ChoD, which is very similar to the Mtb enzyme (70% identity at the amino-acid level), to evaluate...

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Библиографические подробности
Главные авторы: Bednarska, Katarzyna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw, Klink, Magdalena
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121183/
https://ncbi.nlm.nih.gov/pubmed/25120288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/498395
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