Developmental Fate and Cellular Maturity Encoded in Human Regulatory DNA Landscapes

Cellular-state information between generations of developing cells may be propagated via regulatory regions. We report consistent patterns of gain and loss of DNase I-hypersensitive sites (DHSs) as cells progress from embryonic stem cells (ESCs) to terminal fates. DHS patterns alone convey rich info...

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Bibliografski detalji
Glavni autori: Stergachis, Andrew B., Neph, Shane, Reynolds, Alex, Humbert, Richard, Miller, Brady, Paige, Sharon L., Vernot, Benjamin, Cheng, Jeffrey B., Thurman, Robert E., Sandstrom, Richard, Haugen, Eric, Heimfeld, Shelly, Murry, Charles E., Akey, Joshua M., Stamatoyannopoulos, John A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962256/
https://ncbi.nlm.nih.gov/pubmed/23953118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.07.020
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