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Topoisomerase II and leukemia

Type II topoisomerases are essential enzymes that modulate DNA under- and overwinding, knotting, and tangling. Beyond their critical physiological functions, these enzymes are the targets for some of the most widely prescribed anticancer drugs (topoisomerase II poisons) in clinical use. Topoisomeras...

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Bibliografische gegevens
Hoofdauteurs: Pendleton, MaryJean, Lindsey, R. Hunter, Felix, Carolyn A., Grimwade, David, Osheroff, Neil
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961513/
https://ncbi.nlm.nih.gov/pubmed/24495080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12358
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