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Topoisomerase II and leukemia

Type II topoisomerases are essential enzymes that modulate DNA under- and overwinding, knotting, and tangling. Beyond their critical physiological functions, these enzymes are the targets for some of the most widely prescribed anticancer drugs (topoisomerase II poisons) in clinical use. Topoisomeras...

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Podrobná bibliografie
Hlavní autoři: Pendleton, MaryJean, Lindsey, R. Hunter, Felix, Carolyn A., Grimwade, David, Osheroff, Neil
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961513/
https://ncbi.nlm.nih.gov/pubmed/24495080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.12358
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