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Enantioselective Diels–Alder reactions catalyzed by hydrogen bonding

Like molecules of life (e.g., proteins and DNA), many pharmaceutical drugs are also asymmetric (chiral); they are not superimposable on their mirror images. One mirror image form (enantiomer) of a drug can have desirable activity, the other not. Consequently, the development of methods for the selec...

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Autores principales: Thadani, Avinash N., Stankovic, Ana R., Rawal, Viresh H.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC395998/
https://ncbi.nlm.nih.gov/pubmed/15069185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308545101
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