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Enantioselective Diels–Alder reactions catalyzed by hydrogen bonding
Like molecules of life (e.g., proteins and DNA), many pharmaceutical drugs are also asymmetric (chiral); they are not superimposable on their mirror images. One mirror image form (enantiomer) of a drug can have desirable activity, the other not. Consequently, the development of methods for the selec...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395998/ https://ncbi.nlm.nih.gov/pubmed/15069185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308545101 |
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