Enantioselective direct aldol reactions catalyzed by l-prolinamide derivatives
l-Prolinamides 2, prepared from l-proline and simple aliphatic and aromatic amines, have been found to be active catalysts for the direct aldol reaction of 4-nitrobenzaldehyde with neat acetone at room temperature. They give moderate enantioselectivities of up to 46% enantiomeric excess (ee). The en...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15079057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307176101 |
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