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Enantioselective direct aldol reactions catalyzed by l-prolinamide derivatives
l-Prolinamides 2, prepared from l-proline and simple aliphatic and aromatic amines, have been found to be active catalysts for the direct aldol reaction of 4-nitrobenzaldehyde with neat acetone at room temperature. They give moderate enantioselectivities of up to 46% enantiomeric excess (ee). The en...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395980/ https://ncbi.nlm.nih.gov/pubmed/15079057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307176101 |
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