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Enantioselective direct aldol reactions catalyzed by l-prolinamide derivatives

l-Prolinamides 2, prepared from l-proline and simple aliphatic and aromatic amines, have been found to be active catalysts for the direct aldol reaction of 4-nitrobenzaldehyde with neat acetone at room temperature. They give moderate enantioselectivities of up to 46% enantiomeric excess (ee). The en...

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Hlavní autoři: Tang, Zhuo, Jiang, Fan, Cui, Xin, Gong, Liu-Zhu, Mi, Ai-Qiao, Jiang, Yao-Zhong, Wu, Yun-Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC395980/
https://ncbi.nlm.nih.gov/pubmed/15079057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307176101
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