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Hydrogen Bond Catalyzed Enantioselective Vinylogous Mukaiyama Aldol Reaction

[Image: see text] The concept of hydrogen bonding catalysis was extended to the vinylogous Mukaiyama aldol reaction, which gives rapid access to polyketide derivatives. The reaction of the silyldienol ether shown and a range of aldehydes catalyzed by TADDOL proceeds regiospecifically to produce the...

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Bibliographic Details
Main Authors: Gondi, Vijaya Bhasker, Gravel, Michel, Rawal, Viresh H.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2537470/
https://ncbi.nlm.nih.gov/pubmed/16321015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol052301p
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