miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway

Wnt/β-catenin signaling underlies the pathogenesis of a broad range of human cancers, including the deadly plasma cell cancer multiple myeloma (MM). In this study, we report that downregulation of the tumor suppressor microRNA miR-30-5p is a frequent pathogenetic event in MM. Evidence was developed...

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Detalhes bibliográficos
Main Authors: Zhao, Jian-Jun, Lin, Jianhong, Zhu, Di, Wang, Xujun, Brooks, Daniel, Chen, Ming, Chu, Zhang-Bo, Takada, Kohichi, Ciccarelli, Bryan, Admin, Samir, Tao, Jianguo, Tai, Yu-Tzu, Treon, Steven, Pinkus, Geraldine, Kuo, Winston Patrick, Hideshima, Teru, Bouxsein, Mary, Munshi, Nikhil, Anderson, Kenneth, Carrasco, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959627/
https://ncbi.nlm.nih.gov/pubmed/24599134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3311-T
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