Cytotoxic Effects of the Radiocontrast Agent Iotrolan and Anesthetic Agents Bupivacaine and Lidocaine in Three-Dimensional Cultures of Human Intervertebral Disc Nucleus Pulposus Cells: Identification of the Apoptotic Pathways

BACKGROUND: Discography and discoblock are imaging procedures used to diagnose discogenic low back pain. Although needle puncture of the intervertebral disc (IVD) itself induces disc degeneration, the agents used in these procedures may also have harmful effects on IVD cells. The purpose of this stu...

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Detalhes bibliográficos
Main Authors: Iwasaki, Koji, Sudo, Hideki, Yamada, Katsuhisa, Ito, Manabu, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958541/
https://ncbi.nlm.nih.gov/pubmed/24642945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092442
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