Effects of Single Injection of Local Anesthetic Agents on Intervertebral Disc Degeneration: Ex Vivo and Long-Term In Vivo Experimental Study

BACKGROUND: Analgesic discography (discoblock) can be used to diagnose or treat discogenic low back pain by injecting a small amount of local anesthetics. However, recent in vitro studies have revealed cytotoxic effects of local anesthetics on intervertebral disc (IVD) cells. Here we aimed to invest...

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Main Authors: Iwasaki, Koji, Sudo, Hideki, Yamada, Katsuhisa, Higashi, Hideaki, Ohnishi, Takashi, Tsujimoto, Takeru, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186881/
https://ncbi.nlm.nih.gov/pubmed/25286407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109851
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