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Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model

BACKGROUND: Intervertebral disc degeneration is a significant cause of degenerative spinal diseases. Nucleus pulposus (NP) cells reportedly fail to survive in large degenerated discs with limited nutrient availability. Therefore, understanding the regulatory mechanism of the molecular response of NP...

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Bibliografiske detaljer
Main Authors: Sudo, Hideki, Yamada, Katsuhisa, Iwasaki, Koji, Higashi, Hideaki, Ito, Manabu, Minami, Akio, Iwasaki, Norimasa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592817/
https://ncbi.nlm.nih.gov/pubmed/23520533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058806
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