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Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model

BACKGROUND: Intervertebral disc degeneration is a significant cause of degenerative spinal diseases. Nucleus pulposus (NP) cells reportedly fail to survive in large degenerated discs with limited nutrient availability. Therefore, understanding the regulatory mechanism of the molecular response of NP...

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Detalhes bibliográficos
Main Authors: Sudo, Hideki, Yamada, Katsuhisa, Iwasaki, Koji, Higashi, Hideaki, Ito, Manabu, Minami, Akio, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592817/
https://ncbi.nlm.nih.gov/pubmed/23520533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058806
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