Global Identification of Genes Related to Nutrient Deficiency in Intervertebral Disc Cells in an Experimental Nutrient Deprivation Model

BACKGROUND: Intervertebral disc degeneration is a significant cause of degenerative spinal diseases. Nucleus pulposus (NP) cells reportedly fail to survive in large degenerated discs with limited nutrient availability. Therefore, understanding the regulatory mechanism of the molecular response of NP...

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Main Authors: Sudo, Hideki, Yamada, Katsuhisa, Iwasaki, Koji, Higashi, Hideaki, Ito, Manabu, Minami, Akio, Iwasaki, Norimasa
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592817/
https://ncbi.nlm.nih.gov/pubmed/23520533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058806
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