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Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

BACKGROUND: Because the regenerative ability of intervertebral discs (IVDs) is restricted, defects caused by discectomy may induce insufficient tissue repair leading to further IVD degeneration. An acellular bioresorbable biomaterial based on ultra-purified alginate (UPAL) gel was developed to fill...

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Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Ukeba, Daisuke, Sudo, Hideki, Tsujimoto, Takeru, Ura, Katsuro, Yamada, Katsuhisa, Iwasaki, Norimasa
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057222/
https://ncbi.nlm.nih.gov/pubmed/32143180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102698
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