Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

BACKGROUND: Because the regenerative ability of intervertebral discs (IVDs) is restricted, defects caused by discectomy may induce insufficient tissue repair leading to further IVD degeneration. An acellular bioresorbable biomaterial based on ultra-purified alginate (UPAL) gel was developed to fill...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Ukeba, Daisuke, Sudo, Hideki, Tsujimoto, Takeru, Ura, Katsuro, Yamada, Katsuhisa, Iwasaki, Norimasa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057222/
https://ncbi.nlm.nih.gov/pubmed/32143180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102698
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