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Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

BACKGROUND: Because the regenerative ability of intervertebral discs (IVDs) is restricted, defects caused by discectomy may induce insufficient tissue repair leading to further IVD degeneration. An acellular bioresorbable biomaterial based on ultra-purified alginate (UPAL) gel was developed to fill...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ukeba, Daisuke, Sudo, Hideki, Tsujimoto, Takeru, Ura, Katsuro, Yamada, Katsuhisa, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057222/
https://ncbi.nlm.nih.gov/pubmed/32143180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102698
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