A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila

The small GTPase RAS is among the most prevalent oncogenes. The evolutionarily conserved RAF-MEK-MAPK module that lies downstream of RAS is one of the main conduits through which RAS transmits proliferative signals in normal and cancer cells. Genetic and biochemical studies conducted over the last t...

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Detalhes bibliográficos
Main Authors: Ashton-Beaucage, Dariel, Udell, Christian M., Gendron, Patrick, Sahmi, Malha, Lefrançois, Martin, Baril, Caroline, Guenier, Anne-Sophie, Duchaine, Jean, Lamarre, Daniel, Lemieux, Sébastien, Therrien, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958334/
https://ncbi.nlm.nih.gov/pubmed/24643257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001809
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