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Apical Accumulation of the Sevenless Receptor Tyrosine Kinase During Drosophila Eye Development Is Promoted by the Small GTPase Rap1

The Ras/MAPK-signaling pathway plays pivotal roles during development of metazoans by controlling cell proliferation and cell differentiation elicited, in several instances, by receptor tyrosine kinases (RTKs). While the internal mechanism of RTK-driven Ras/MAPK signaling is well understood, far les...

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Detalhes bibliográficos
Main Authors: Baril, Caroline, Lefrançois, Martin, Sahmi, Malha, Knævelsrud, Helene, Therrien, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125397/
https://ncbi.nlm.nih.gov/pubmed/24899161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.166272
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