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Apical Accumulation of the Sevenless Receptor Tyrosine Kinase During Drosophila Eye Development Is Promoted by the Small GTPase Rap1

The Ras/MAPK-signaling pathway plays pivotal roles during development of metazoans by controlling cell proliferation and cell differentiation elicited, in several instances, by receptor tyrosine kinases (RTKs). While the internal mechanism of RTK-driven Ras/MAPK signaling is well understood, far les...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baril, Caroline, Lefrançois, Martin, Sahmi, Malha, Knævelsrud, Helene, Therrien, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125397/
https://ncbi.nlm.nih.gov/pubmed/24899161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.166272
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