Identification of Polo-like kinase 1 interaction inhibitors using a novel cell-based assay

door Normandin, Karine, Lavallée, Jean-François, Futter, Marie, Beautrait, Alexandre, Duchaine, Jean, Guiral, Sébastien, Marinier, Anne, Archambault, Vincent
Gepubliceerd in Sci Rep (2016)

Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization

door Lavoie, Hugo, Thevakumaran, Neroshan, Gavory, Gwenaëlle, Li, John, Padeganeh, Abbas, Guiral, Sébastien, Duchaine, Jean, Mao, Daniel Y. L., Bouvier, Michel, Sicheri, Frank, Therrien, Marc
Gepubliceerd in Nat Chem Biol (2013)

A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila

door Ashton-Beaucage, Dariel, Udell, Christian M., Gendron, Patrick, Sahmi, Malha, Lefrançois, Martin, Baril, Caroline, Guenier, Anne-Sophie, Duchaine, Jean, Lamarre, Daniel, Lemieux, Sébastien, Therrien, Marc
Gepubliceerd in 2014

Genome-wide RNAi Screen Reveals a New Role of a WNT/CTNNB1 Signaling Pathway as Negative Regulator of Virus-induced Innate Immune Responses

door Baril, Martin, Es-Saad, Salwa, Chatel-Chaix, Laurent, Fink, Karin, Pham, Tram, Raymond, Valérie-Ann, Audette, Karine, Guenier, Anne-Sophie, Duchaine, Jean, Servant, Marc, Bilodeau, Marc, Cohen, Éric, Grandvaux, Nathalie, Lamarre, Daniel
Gepubliceerd in 2013

Human models of NUP98-KDM5A megakaryocytic leukemia in mice contribute to uncovering new biomarkers and therapeutic vulnerabilities

door Cardin, Sophie, Bilodeau, Mélanie, Roussy, Mathieu, Aubert, Léo, Milan, Thomas, Jouan, Loubna, Rouette, Alexandre, Laramée, Louise, Gendron, Patrick, Duchaine, Jean, Decaluwe, Hélène, Spinella, Jean-François, Mourad, Stéphanie, Couture, Françoise, Sinnett, Daniel, Haddad, Élie, Landry, Josette-Renée, Ma, Jing, Humphries, R. Keith, Roux, Philippe P., Hébert, Josée, Gruber, Tanja A., Wilhelm, Brian T., Cellot, Sonia
Gepubliceerd in Blood Adv (2019)