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Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair
DNA nicks are the most common form of DNA damage, and if unrepaired can give rise to genomic instability. In human cells, nicks are efficiently repaired via the single-strand break repair pathway, but relatively little is known about the fate of nicks not processed by that pathway. Here we show that...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956201/ https://ncbi.nlm.nih.gov/pubmed/24556991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400236111 |
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