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Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair

DNA nicks are the most common form of DNA damage, and if unrepaired can give rise to genomic instability. In human cells, nicks are efficiently repaired via the single-strand break repair pathway, but relatively little is known about the fate of nicks not processed by that pathway. Here we show that...

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Bibliografski detalji
Glavni autori: Davis, Luther, Maizels, Nancy
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956201/
https://ncbi.nlm.nih.gov/pubmed/24556991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400236111
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