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Two Distinct Pathways Support Gene Correction by Single-stranded Donors at DNA Nicks
Nicks are the most common form of DNA damage. The mechanisms of their repair are fundamental to genomic stability, and of practical importance for genome engineering. We define two pathways that support homology-directed repair by single-stranded DNA donors. One depends upon annealing-driven strand...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108528/ https://ncbi.nlm.nih.gov/pubmed/27829157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.049 |
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