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Two Distinct Pathways Support Gene Correction by Single-stranded Donors at DNA Nicks

Nicks are the most common form of DNA damage. The mechanisms of their repair are fundamental to genomic stability, and of practical importance for genome engineering. We define two pathways that support homology-directed repair by single-stranded DNA donors. One depends upon annealing-driven strand...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Davis, Luther, Maizels, Nancy
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108528/
https://ncbi.nlm.nih.gov/pubmed/27829157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.049
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