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Pathways and signatures of mutagenesis at targeted DNA nicks
Nicks are the most frequent form of DNA damage and a potential source of mutagenesis in human cells. By deep sequencing, we have identified factors and pathways that promote and limit mutagenic repair at a targeted nick in human cells. Mutations were distributed asymmetrically around the nick site....
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8078790/ https://ncbi.nlm.nih.gov/pubmed/33857147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009329 |
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