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Pathways and signatures of mutagenesis at targeted DNA nicks
Nicks are the most frequent form of DNA damage and a potential source of mutagenesis in human cells. By deep sequencing, we have identified factors and pathways that promote and limit mutagenic repair at a targeted nick in human cells. Mutations were distributed asymmetrically around the nick site....
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8078790/ https://ncbi.nlm.nih.gov/pubmed/33857147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009329 |
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