Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke – induced pulmonary injury and emphysema

Rtp801, a stress – related protein triggered by adverse environmental conditions, inhibits mTOR and enhances oxidative stress – dependent cell death. We postulated that Rtp801 acts as potential amplifying switch in the development of cigarette smoke – induced lung injury, leading to emphysema. Rtp80...

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Bibliografische gegevens
Hoofdauteurs: Yoshida, Toshinori, Mett, Igor, Bhunia, Anil K., Bowman, Joel, Perez, Mario, Zhang, Li, Gandjeva, Aneta, Zhen, Lijie, Chukwueke, Ugonma, Mao, Thianzi, Richter, Amy, Brown, Emile, Ashush, Hagit, Notkin, Natalie, Gelfand, Anna, Thimmulappa, Rajesh K, Rangasamy, Tirumalai, Sussman, Thomas, Cosgrove, Gregory, Mouded, Majd, Shapiro, Steven D, Petrache, Irina, Biswal, Shyam, Feinstein, Elena, Tuder, Rubin M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956129/
https://ncbi.nlm.nih.gov/pubmed/20473305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2157
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