Rtp801 Suppression of Epithelial mTORC1 Augments Endotoxin-Induced Lung Inflammation

The mechanistic target of rapamycin (mTOR) is a central regulator of cellular responses to environmental stress. mTOR (and its primary complex mTORC1) is, therefore, ideally positioned to regulate lung inflammatory responses to an environmental insult, a function directly relevant to disease states...

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Detalhes bibliográficos
Main Authors: Nadon, Aaron M., Perez, Mario J., Hernandez-Saavedra, Daniel, Smith, Lynelle P., Yang, Yimu, Sanders, Linda A., Gandjeva, Aneta, Chabon, Jacob, Koyanagi, Daniel E., Graham, Brian B., Tuder, Rubin M., Schmidt, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188171/
https://ncbi.nlm.nih.gov/pubmed/25016184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.002
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