DDIT4/REDD1/RTP801 Is a Novel Negative Regulator of Schwann Cell Myelination

Signals that promote myelination must be tightly modulated to adjust myelin thickness to the axonal diameter. In the peripheral nervous system, axonal neuregulin 1 type III promotes myelination by activating erbB2/B3 receptors and the PI3K/AKT/mTOR pathway in Schwann cells. Conversely, PTEN (phospha...

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Hlavní autoři: Noseda, Roberta, Belin, Sophie, Piguet, Françoise, Vaccari, Ilaria, Scarlino, Stefania, Brambilla, Paola, Boneschi, Filippo Martinelli, Feltri, Maria Laura, Wrabetz, Lawrence, Quattrini, Angelo, Feinstein, Elena, Huganir, Richard L., Bolino, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988321/
https://ncbi.nlm.nih.gov/pubmed/24048858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2408-13.2013
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