Glucocorticoid Elevation of Dexamethasone-induced Gene 2 (Dig2/RTP801/REDD1) Protein Mediates Autophagy in Lymphocytes

Glucocorticoid hormones, including dexamethasone, induce apoptosis in lymphocytes and consequently are used clinically as chemotherapeutic agents in many hematologic malignancies. Dexamethasone also induces autophagy in lymphocytes, although the mechanism is not fully elucidated. Through gene expres...

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מידע ביבליוגרפי
Main Authors: Molitoris, Jason K., McColl, Karen S., Swerdlow, Sarah, Matsuyama, Mieko, Lam, Minh, Finkel, Terri H., Matsuyama, Shigemi, Distelhorst, Clark W.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
Cell Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191057/
https://ncbi.nlm.nih.gov/pubmed/21733849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.245423
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