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The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6.

A major challenge in basic and applied biological research is the engineering of small proteins with pre-determined structures and novel functions. In a limited number of cases, this has been achieved by de novo design. An alternative combinatorial approach is based on the construction of large libr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martin, F, Toniatti, C, Salvati, A L, Venturini, S, Ciliberto, G, Cortese, R, Sollazzo, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395486/
https://ncbi.nlm.nih.gov/pubmed/7957096
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