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The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6.

A major challenge in basic and applied biological research is the engineering of small proteins with pre-determined structures and novel functions. In a limited number of cases, this has been achieved by de novo design. An alternative combinatorial approach is based on the construction of large libr...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Martin, F, Toniatti, C, Salvati, A L, Venturini, S, Ciliberto, G, Cortese, R, Sollazzo, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7957096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06864.x
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