Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires.

Given the extent of hepatitis C virus (HCV) infection as a worldwide health problem and the lack of effective treatment, the development of anti-HCV drugs is an important and pressing objective. Previous studies have indicated that proteolytic events mediated by the NS3 protease of HCV are fundament...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dimasi, N, Martin, F, Volpari, C, Brunetti, M, Biasiol, G, Altamura, S, Cortese, R, De Francesco, R, Steinkühler, C, Sollazzo, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7461-7469.1997
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