Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires.

Given the extent of hepatitis C virus (HCV) infection as a worldwide health problem and the lack of effective treatment, the development of anti-HCV drugs is an important and pressing objective. Previous studies have indicated that proteolytic events mediated by the NS3 protease of HCV are fundament...

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Autors principals: Dimasi, N, Martin, F, Volpari, C, Brunetti, M, Biasiol, G, Altamura, S, Cortese, R, De Francesco, R, Steinkühler, C, Sollazzo, M
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC192092/
https://ncbi.nlm.nih.gov/pubmed/9311825
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