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tris-Azaaromatic quaternary ammonium salts: novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release

A series of tris-azaaromatic quaternary ammonium salts has been synthesized and evaluated for their ability to inhibit neuronal nicotinic acetylcholine receptors (nAChRs) mediating nicotine-evoked [(3)H]dopamine release from superfused rat striatal slices and for inhibition of [(3)H]nicotine and [(3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Guangrong, Sumithran, Sangeetha P., Deaciuc, Agripina G., Dwoskin, Linda P., Crooks, Peter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954472/
https://ncbi.nlm.nih.gov/pubmed/17977723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.10.062
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