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Novel bis-, tris-, and tetrakis-tertiary amino analogues as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release
A series of tertiary amine analogues derived from lead azaaromatic quaternary ammonium salts has been designed and synthesized. The preliminary structure-activity relationships of these new analogues suggest that such tertiary amine analogues, which potently inhibit nicotine-evoked dopamine release...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725996/ https://ncbi.nlm.nih.gov/pubmed/21147530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.11.070 |
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