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tetrakis-Azaaromatic quaternary ammonium salts: Novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release
A series of tetrakis-azaaromatic quaternary ammonium salts was synthesized in order to identify compounds with higher affinity and selectivity as antagonists at neuronal nicotinic receptor subtypes that mediate nicotine-evoked DA release. A high hit rate was achieved in identifying potent analogues...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437627/ https://ncbi.nlm.nih.gov/pubmed/18851914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.09.084 |
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