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Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.
The requirement for a functional retinoblastoma gene, Rb-1, in murine development around days 12-15 of gestation precludes monitoring the effect of loss of Rb-1 function on later stages of development and on tumorigenesis in adult mice. Here we describe the developmental rescue of embryonic stem cel...
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Main Authors: | , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
1994
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395353/ https://ncbi.nlm.nih.gov/pubmed/7925271 |
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