Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.

A vast amount of data suggests that homologous recombination in mammalian cells is relatively rare as compared to random integration, imposing the need for sophisticated selection protocols to enrich for cells in which homologous recombination has occurred. We here show that one of the key factors i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: te Riele, H, Maandag, E R, Berns, A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1992
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC49242/
https://ncbi.nlm.nih.gov/pubmed/1594621
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