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The role and fate of DNA ends for homologous recombination in embryonic stem cells.

We have analyzed the gene-targeting frequencies and recombination products generated by a series of vectors which target the hprt locus in embryonic stem cells and found the existence of alternative pathways that depend on the location of the double-strand break within the vector. A double-strand br...

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Sonraí Bibleagrafaíochta
Main Authors: Hasty, P, Rivera-Pérez, J, Bradley, A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1992
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC364439/
https://ncbi.nlm.nih.gov/pubmed/1588950
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