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The role and fate of DNA ends for homologous recombination in embryonic stem cells.

We have analyzed the gene-targeting frequencies and recombination products generated by a series of vectors which target the hprt locus in embryonic stem cells and found the existence of alternative pathways that depend on the location of the double-strand break within the vector. A double-strand br...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Hasty, P, Rivera-Pérez, J, Bradley, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1588950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2464-2474.1992
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