Fidelity of targeted recombination in human fibroblasts and murine embryonic stem cells.

Targeted recombination in murine embryonic stem cells promises to be a powerful tool for introducing specific mutations into target genes to study development in mice and to create animal models of human disease. Gene targeting also holds potential for correcting genetic defects as an approach to hu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zheng, H, Hasty, P, Brenneman, M A, Grompe, M, Gibbs, R A, Wilson, J H, Bradley, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1896453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8067
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