Fidelity of targeted recombination in human fibroblasts and murine embryonic stem cells.

Targeted recombination in murine embryonic stem cells promises to be a powerful tool for introducing specific mutations into target genes to study development in mice and to create animal models of human disease. Gene targeting also holds potential for correcting genetic defects as an approach to hu...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Zheng, H, Hasty, P, Brenneman, M A, Grompe, M, Gibbs, R A, Wilson, J H, Bradley, A
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1896453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8067
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