The role and fate of DNA ends for homologous recombination in embryonic stem cells.
We have analyzed the gene-targeting frequencies and recombination products generated by a series of vectors which target the hprt locus in embryonic stem cells and found the existence of alternative pathways that depend on the location of the double-strand break within the vector. A double-strand br...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1588950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.6.2464-2474.1992 |
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