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Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms
We report the three-dimensional structure of human neonatal Fc receptor (FcRn) bound concurrently to its two known ligands. More particularly, we solved the crystal structure of the complex between human FcRn, wild-type human serum albumin (HSA), and a human Fc engineered for improved pharmacokineti...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953293/ https://ncbi.nlm.nih.gov/pubmed/24469444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537563 |
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