A Role for Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) in the Regulation of Hepatic Gluconeogenesis

Synthesis of phosphoenolpyruvate (PEP) from oxaloacetate is an absolute requirement for gluconeogenesis from mitochondrial substrates. Generally, this reaction has solely been attributed to the cytosolic isoform of PEPCK (PEPCK-C), although loss of the mitochondrial isoform (PEPCK-M) has never been...

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Detalhes bibliográficos
Main Authors: Stark, Romana, Guebre-Egziabher, Fitsum, Zhao, Xiaojian, Feriod, Colleen, Dong, Jianying, Alves, Tiago C., Ioja, Simona, Pongratz, Rebecca L., Bhanot, Sanjay, Roden, Michael, Cline, Gary W., Shulman, Gerald I., Kibbey, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953244/
https://ncbi.nlm.nih.gov/pubmed/24497630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.544759
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