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The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?

BACKGROUND: Plasma glucose levels are tightly regulated within a narrow physiologic range. Insulin-mediated glucose uptake by tissues must be balanced by the appearance of glucose from nutritional sources, glycogen stores, or gluconeogenesis. In this regard, a common pathway regulating both glucose...

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Detalhes bibliográficos
Main Authors: Stark, Romana, Kibbey, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943549/
https://ncbi.nlm.nih.gov/pubmed/24177027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.10.033
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