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Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis

BACKGROUND: Phosphoenolpyruvate carboxykinase (PCK) has been almost exclusively recognized as a critical enzyme in gluconeogenesis, especially in the liver and kidney. Accumulating evidence has shown that the enhanced activity of PCK leads to increased glucose output and exacerbation of diabetes, wh...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Yu, Shuo, Meng, Simin, Xiang, Meixiang, Ma, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190478/
https://ncbi.nlm.nih.gov/pubmed/34020084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101257
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