Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation

Acute intestinal inflammation involves early accumulation of neutrophils (PMN) followed by either resolution or progression to chronic inflammation. Based on recent evidence mucosal metabolism influences disease outcomes, we hypothesized that transmigrating PMN influence the transcriptional profile...

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Detalhes bibliográficos
Main Authors: Campbell, Eric L, Bruyninckx, Walter J, Kelly, Caleb J, Glover, Louise E, McNamee, Eóin N, Bowers, Brittelle E, Bayless, Amanda J, Scully, Melanie, Saeedi, Bejan J, Golden-Mason, Lucy, Ehrentraut, Stefan F, Curtis, Valerie F, Burgess, Adrianne, Garvey, John F, Sorensen, Amber, Nemenoff, Raphael, Jedlicka, Paul, Taylor, Cormac T, Kominsky, Douglas J, Colgan, Sean P
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951457/
https://ncbi.nlm.nih.gov/pubmed/24412613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.11.020
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