Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation

Acute intestinal inflammation involves early accumulation of neutrophils (PMN) followed by either resolution or progression to chronic inflammation. Based on recent evidence mucosal metabolism influences disease outcomes, we hypothesized that transmigrating PMN influence the transcriptional profile...

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Détails bibliographiques
Auteurs principaux: Campbell, Eric L, Bruyninckx, Walter J, Kelly, Caleb J, Glover, Louise E, McNamee, Eóin N, Bowers, Brittelle E, Bayless, Amanda J, Scully, Melanie, Saeedi, Bejan J, Golden-Mason, Lucy, Ehrentraut, Stefan F, Curtis, Valerie F, Burgess, Adrianne, Garvey, John F, Sorensen, Amber, Nemenoff, Raphael, Jedlicka, Paul, Taylor, Cormac T, Kominsky, Douglas J, Colgan, Sean P
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951457/
https://ncbi.nlm.nih.gov/pubmed/24412613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.11.020
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