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NBN Phosphorylation regulates the accumulation of MRN and ATM at sites of DNA Double-Strand Breaks
In response to ionizing radiation, the MRE11/RAD50/NBN (MRN) complex re-distributes to the sites of DNA double strand breaks (DSBs) where each of its individual components is phosphorylated by the serine-threonine kinase, ATM. ATM phosphorylation of NBN is required for activation of the S-phase chec...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951136/ https://ncbi.nlm.nih.gov/pubmed/23146902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.443 |
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