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Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo

MN (motor neuron) death in amyotrophic lateral sclerosis may be mediated by glutamatergic excitotoxicity. Previously, our group showed that the microdialysis perfusion of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionate) in the rat lumbar spinal cord induced MN death and permanent paralysis w...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Santa-Cruz, Luz Diana, Tapia, Ricardo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Neurochemistry 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950966/
https://ncbi.nlm.nih.gov/pubmed/24524836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20130046
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