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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Netzahualcoyotzi, Citlalli, Tapia, Ricardo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224557/
https://ncbi.nlm.nih.gov/pubmed/30410110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35027-w
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