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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224557/ https://ncbi.nlm.nih.gov/pubmed/30410110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35027-w |
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