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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Netzahualcoyotzi, Citlalli, Tapia, Ricardo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224557/
https://ncbi.nlm.nih.gov/pubmed/30410110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35027-w
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