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Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

The tetanus toxin C-fragment is a non-toxic peptide that can be transported from peripheral axons into spinal motoneurons. In in vitro experiments it has been shown that this peptide activates signaling pathways associated with Trk receptors, leading to cellular survival. Because motoneuron degenera...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Netzahualcoyotzi, Citlalli, Tapia, Ricardo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224557/
https://ncbi.nlm.nih.gov/pubmed/30410110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35027-w
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